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Solar Lentigenes

It is also called the Leopard syndrome. Lentigenes means freckle like spots.

Lentigenes are the lesions that may be seen on that part of the body that is often Lentigenesexposed to sunrays most – like hand or face. They present as lesions and are also called liver spots. They are benign in nature and do not become cancerous. Back of the hand and face are the areas where we may usually find these. It is common to see these lesions increases in numbers as the victim ages; thus it is more common among the middle aged and the old. The size of the lesions varies from 0.2 to 2 cm. They are flat and have outline just about discernible; they are dark in color, and have irregular shape.

Causes of Lentigenes:

Sudden and remarkable increase in the pigments cells, which are, located in the superficial layers of the skin cause these lesions. Sometimes the lesions develop into highly irregular shapes, or their color might change, or gain in thickness. At such times, Biopsy has to be made because cancer has to be ruled out. Otherwise, Lentigenes are mostly benign.

Treatment of Lentigenes

They do not even require treatment. When treated, it is usually. for cosmetic reasons. Cryotherapy has been successfully applied; hydroquinone (bleaching powder) preperations, retinoids, chemical peels or lasers are also found to be effective in treatment. Prevention and sustaining the cure is possible through protecting the skin against any excessive exposure with sunscreen and protective clothing. Wearing long sleeves and sun hats protect the susceptible parts of the body.

Some facts about Lentigenes

These freckles are often inherited disorders. They may be present from birth. Inherited as dominant trait. They are quickly perceived as they occur mostly on the trunk and the neck, the freckles darker than the other ordinary ones.
The children suffering from this also have wide set eyes (hypertelorism), prominent ears, partial deafness, and light brown birthmarks.

These are the superficial findings. But additional findings are also there.

Additional findings:

Pulmonic steno is, and changes shown in the ECG. They may also have abnormal genitalia or delayed puberty.
There would be a family history of multiple lentigenes when examining the patient.
There is usually; abnormalities in breast bones, the patient registers slow growth, and at times puberty is delayed or altogether absent.


Physical examination would show mild obstruction of the pulmonic heart valve and obstructive cardiomyopathy. Besides, Electro cardio gram tests and hearing tests must also be performed. Endocrine evaluation tests are to be made.


Hearing disorder can be corrected through appropriate hearing aids according to the degree of loss in hearing. Timely intervention during the age when puberty must occur could effectively rectify the problem and make normal changes to occur.

Response and complications:

Usually the disease responds to treatment well usually. But the lentigenes also result in complications like deafness, heart problems, and infertility.

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